Effect of mind sound resonance technique (msrt: a yogic relaxation technique) on perceived stress, state anxiety & IVF outcome in women undergoing IVF treatment a randomised control study

Abstract

Background The women undergoing infertility treatments are under stress and anxiety. The aim of this study was to see the effect of Mind Sound Resonance Technique (A Yogic Relaxation Technique) on Perceived Stress, State Anxiety and the outcome of IVF in women undergoing IVF treatment. The studies like The prevalence of primary infertility in Mysore by Paul C.Adamson1 and colleagues, Stress and Anxiety during IVF by Kathy Turner2 and colleagues, Influence of stress and anxiety in women entering IVF by Csemiczky G3 and colleagues, etc. done worldwide also show that women undergoing IVF are stressed and anxiety levels are high during different stages of treatment and the effect on the outcome. Method Randomized control study was done on the women patients who started their IVF treatment. State Trait Anxiety Inventory (Spielberger, C.D., Sydeman, S.J. (1994) and Perceived Stress Scale (Cohen & Williamson, 1988) were measured on the first day of hormone stimulation and repeated after Embryo Transfer. Taking the environment of the clinic into consideration, the first 30 women were taken into the control group and the women who came in later were taken into experiment group. The experiment group were given the intervention, Mind Sound Resonance Technique (A Yogic Relaxation) during the stimulation days and on the day of Embryo Transfer. The patient was allowed to record the audio of the intervention and practice the relaxation technique even at home (till they came for the Beta HCG: implantation blood test). Both groups were compared in terms of demographic details and clinical details. The two group study was then related to see the outcome after the treatment. Results Comparison of the demographic details showed no significant difference. The total hormone stimulation also showed no significant difference when compared to both the groups. Both groups were comparative in terms of age, duration of infertility, FSH, AMH, dosage and number of days of stimulation. The quality of the embryos, embryo transferred and embryo frozen did not show significant difference, which means that this study was a very good comparative study. The Student t-test (unpaired) was done on the State anxiety (STAI) score of the patient on the first day of stimulation and after the Embryo Transfer. The p value on the day of stimulation did not show significant difference when compared with the two groups. Whereas, the p value showed strongly significant (0.001**) change in the State anxiety score post Embryo Transfer. The Student t test (unpaired) was done on the Perceived Stress (PSS) score of the patient on the first day of stimulation and after the Embryo Transfer. The p value, on the day of stimulation did not show significant difference when compared with the two groups. Whereas, the p value showed moderate significant (0.037*) change in the Stress score post Embryo Transfer. The Chi-Square test is done to assess the outcome in both the groups. The results were significantly high with the outcome of pregnancy being 9 (30%) positives in control group and 17 (56%) positives in experiment group. The age group was categorized in both experiment group and control group to study the Beta HCG positive outcome. As further test of analysis, when the results were compared according to the different age group categorization, Beta HCG positivity showed a positive trend in the experiment group when compared to the control group though it was not statistically significant. The clinical pregnancy rate shows that experiment group had significantly less number of patients who experienced abortions and significantly more number of patients who achieved clinical pregnancy. Conclusion The findings of the present study show that Mind Sound Resonance Technique (MSRT: A Yogic relaxation) intervention is a good technique to reduces Perceived Stress and State Anxiety in women undergoing IVF treatment, in turn helps in implantation and improving outcome of clinical pregnancy.